Factors Affecting EWS-FLI1 Activity in Ewing's Sarcoma-Reference-Cited by-同舟云学术

Factors Affecting EWS-FLI1 Activity in Ewing's Sarcoma

Published:2011 Issue: Volume:2011 Page:1-11
ISSN:1357-714X
Container-title:Sarcoma
language:en
Short-container-title:Sarcoma

Author:

Herrero-Martin David¹,Fourtouna Argyro¹,Niedan Stephan¹,Riedmann Lucia T.¹,Schwentner Raphaela¹^ORCID,Aryee Dave N. T.¹

Affiliation:

1. Children's Cancer Research Institute, St Anna Kinderkrebsforschung, 1090 Vienna, Austria

Abstract

Ewing's sarcoma family tumors (ESFT) are characterized by specific chromosomal translocations, which give rise to EWS-ETS chimeric proteins. These aberrant transcription factors are the main pathogenic drivers of ESFT. Elucidation of the factors influencing EWS-ETS expression and/or activity will guide the development of novel therapeutic agents against this fatal disease.

Publisher

Hindawi Limited

Subject

Radiology Nuclear Medicine and imaging,Oncology

Link

http://downloads.hindawi.com/journals/sarcoma/2011/352580.pdf

Reference144 articles.

1. Gene fusion with an ETS DNA-binding domain caused by chromosome translocation in human tumours

2. Downstream EWS/FLI1 - upstream Ewing's sarcoma

3. EWS-FLI-1 Expression Triggers a Ewing's Sarcoma Initiation Program in Primary Human Mesenchymal Stem Cells

4. The cancer stem cell paradigm in Ewing’s sarcoma: what can we learn about these rare cells from a rare tumor?

Cited by 19 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Oncomeric Profiles of microRNAs as New Therapeutic Targets for Treatment of Ewing’s Sarcoma: A Composite Review;Genes;2023-09-23

2. Ewing sarcoma from molecular biology to the clinic;Frontiers in Cell and Developmental Biology;2023-09-11

3. MAD2L1 Promotes Ewing's Sarcoma Progression Through AURKA/MYC Axis;2022-12-05

4. Regulation of Metastasis in Ewing Sarcoma;Cancers;2022-10-07

5. Liquid–liquid phase separation in tumor biology;Signal Transduction and Targeted Therapy;2022-07-08