Repeatability and Agreement of Central Vault for Implantable Collamer Lens Obtained by the Tomey OA‐2000 Biometer and Spectralis OCT

Abstract

Objective. To assess repeatability and agreement of central vault for implantable collamer lens (ICL) measured by the Tomey OA‐2000 biometry and Spectralis optical coherence tomography (OCT). Methods. In this prospective study, the central vault was measured by the Tomey OA‐2000 biometer and Spectralis OCT in 84 eyes (43 patients) after ICL implantation at six month follow‐up. Three consecutive scans were obtained by one experienced technician using Tomey OA‐2000 and the Spectralis OCT in the same day. The coefficient of variation (CoV), intraclass correlation coefficient (ICC), within‐subject standard deviation (Sw), and 2.77 Sw were calculated to assess the repeatability and reproducibility. The paired t‐test and Bland–Altman plots were used to analyze the differences and agreements of central vault measured by two devices. Results. Repeatability of the central vault measured by Tomey OA‐2000 biometer and Spectralis OCT showed that the CoV was 2.71% and 1.66%, respectively. The ICC for both devices was 0.996 and 0.999, respectively. The paired t‐test showed that central vault measured by Tomey OA‐2000 biometer was −7.25 ± 23.57 microns lower than that measured by Spectralis OCT (P = 0.006). The mean difference between measurements for Tomey OA‐2000 and ASM‐OCT with 95% limits of agreement (LoAs) was −38.94 to 53.44 μm. Conclusion. Both Tomey OA‐2000 biometer and Spectralis OCT displayed good repeatability for the measurement of central vault of ICL. Good reliability and agreement were observed between Tomey OA‐2000 biometer and Spectralis OCT. Both instruments are useful but not replaced each other for central vault measurements.