Quetiapine and Wolff-Parkinson-White Syndrome

Author:

Chen Michael1,Gomaa Hassaan2,Cortez-Resendiz Alonso2,Martin Christopher3,Francis Andrew2,Bellon Alfredo24ORCID

Affiliation:

1. Department of Psychiatry, Lehigh Valley Health Network, 2545 Schoenersville road, Bethlehem PA 18017, USA

2. Department of Psychiatry and Behavioral Health, Penn State Hershey Medical Center, 500 University Drive P.O. Box 850. Mail Code R130. Hershey, PA 17033-0850, USA

3. Department of Psychiatry, Thomas Jefferson University, Philadelphia, PA, USA

4. Department of Pharmacology, Penn State College of Medicine, Penn State Hershey Medical Center, Hershey, PA, USA

Abstract

Quetiapine is occasionally associated with cardiovascular adverse effects such as QTc prolongation. QTc prolongation is a side effect that requires monitoring in order to avoid more serious cardiac complications. One particular understudied area is the potential for antipsychotics to elicit electroconduction abnormalities in patients with Wolff-Parkinson-White (WPW) Syndrome. In the present report, we describe a case of quetiapine overdose in a patient with WPW.

Funder

Penn State IRB

Publisher

Hindawi Limited

Subject

Psychiatry and Mental health

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