Secondary Myelitis in Dermal Sinus Causing Paraplegia in a Child with Previously Normal Neurological Function

Author:

Rashid Sakina1,Kinabo Grace1,Kellogg Marissa2,Howlett William P.3,Dekker Marieke C. J.134ORCID

Affiliation:

1. Department of Pediatrics, Kilimanjaro Christian Medical Centre, Moshi, Tanzania

2. Stanford University, Palo Alto, CA, USA

3. Department of Internal Medicine, Kilimanjaro Christian Medical Centre, Moshi, Tanzania

4. Radboud University Medical Centre, Nijmegen, Netherlands

Abstract

Neural tube defects result from failure of neural tube fusion during early embryogenesis, the fourth week after conception. The spectrum of severity is not uniform across the various forms of this congenital anomaly as certain presentations are not compatible with extrauterine life (anencephaly) while, on the other hand, other defects may remain undiagnosed as they are entirely asymptomatic (occult spina bifida). We report a child with previously normal neurological development, a devastating clinical course following superinfection of a subtle spina bifida defect which resulted in a flaccid paralysis below the level of the lesion and permanent neurological deficits following resolution of the acute infection and a back closure surgery.

Publisher

Hindawi Limited

Subject

General Medicine

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1. Complicated congenital dermal sinus: Diagnosis and management;Interdisciplinary Neurosurgery;2020-09

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