Affiliation:
1. Department of Chemistry, Woldia University, P.O.Box 400, Woldia, Ethiopia
Abstract
Sequential extraction of the roots of Kniphofia insignis using cold maceration techniques and column chromatographic separation leads to the isolation of one monomeric anthraquinone, chrysophanol (1). The structure of the compound was established using spectroscopic analyses including NMR (1H and 13C-NMR, infrared) and comparison with reported literature. The in vitro antibacterial activities of the crude extracts and the isolated compounds were evaluated against four bacterial strains (S. aureus ATCC 25923, B. subtilis ATCC 6633, E. coli ATCC 35218, and P. aeruginosa ATCC 27853). Among them, the crude extract, acetone extract, has shown substantial antibacterial activity with the highest activity against E. coli (22.3 mm). However, compound 1 has a better zone of inhibition with 19.3 mm against P. aeruginosa.
Reference11 articles.
1. AbdissaN.“Phytochemical Investigation of Four Asphodelaceae Plants for Antiplasmodial Principles”2014thesis, Nairobi, KenyaUniversity of NairobiPhD Thesis
2. GebruM.Phytochemical and Antiplasmodial Investigation of Rhamnus and Kniphofia Foliosa2010thesis, Nairobi, KenyaUniversity of NairobiMSc Thesis
3. Anthraquinones as taxonomic markers in ethiopian Kniphofia species
4. Chemical constituent of the roots of Kniphofia isoetifolia hocusht and evaluation for antibacterial activities;M. Meshesha;J. pharm pharmacogn res,.,2017
Cited by
3 articles.
订阅此论文施引文献
订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献