Intrapleural Tenecteplase for Complicated Parapneumonic Pleural Effusion

Author:

Kadhem Husain1ORCID,Sridharan Kannan2ORCID,Naser Naser1

Affiliation:

1. Department of Internal Medicine, Salmaniya Medical Complex, Manama, Bahrain

2. Department of Pharmacology & Therapeutics, College of Medicine & Medical Sciences, Arabian Gulf University, Manama, Bahrain

Abstract

Intrapleural thrombolytics have shown promising results in complicated parapneumonic pleural effusions reducing the need for surgical interventions. Until now, studies have evaluated primarily streptokinase, urokinase, and recently, alteplase. In this case series, we share our experience with tenecteplase—a tissue-specific plasminogen activator in 15 patients. We observed that tenecteplase is effective in 14/15 (93.3%) of our patients, and none of them had any bleeding episodes.

Publisher

Hindawi Limited

Subject

Pulmonary and Respiratory Medicine

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