A Review on Antibacterial, Antiviral, and Antifungal Activity of Curcumin

Author:

Zorofchian Moghadamtousi Soheil1,Abdul Kadir Habsah1,Hassandarvish Pouya2,Tajik Hassan3,Abubakar Sazaly2,Zandi Keivan24

Affiliation:

1. Biomolecular Research Group, Biochemistry Program, Institute of Biological Sciences, Faculty of Science, University of Malaya, 50603 Kuala Lumpur, Malaysia

2. Tropical Infectious Disease Research and Education Center (TIDREC), Department of Medical Microbiology, Faculty of Medicine, University of Malaya, 50603 Kuala Lumpur, Malaysia

3. Department of Chemistry, Faculty of Sciences, Guilan University, Rasht, Iran

4. Persian Gulf Marine Biotechnology Research Center, Bushehr University of Medical Sciences, Bushehr 3631, Iran

Abstract

Curcuma longaL. (Zingiberaceae family) and its polyphenolic compound curcumin have been subjected to a variety of antimicrobial investigations due to extensive traditional uses and low side effects. Antimicrobial activities for curcumin and rhizome extract ofC. longaagainst different bacteria, viruses, fungi, and parasites have been reported. The promising results for antimicrobial activity of curcumin made it a good candidate to enhance the inhibitory effect of existing antimicrobial agents through synergism. Indeed, different investigations have been done to increase the antimicrobial activity of curcumin, including synthesis of different chemical derivatives to increase its water solubility as well ass cell up take of curcumin. This review aims to summarize previous antimicrobial studies of curcumin towards its application in the future studies as a natural antimicrobial agent.

Funder

University Malaya Research

Publisher

Hindawi Limited

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

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