Synthesis and Antimicrobial Activity of a Silver-Hydroxyapatite Nanocomposite-Reference-Cited by-同舟云学术

Synthesis and Antimicrobial Activity of a Silver-Hydroxyapatite Nanocomposite

Published:2009 Issue: Volume:2009 Page:1-6
ISSN:1687-4110
Container-title:Journal of Nanomaterials
language:en
Short-container-title:Journal of Nanomaterials

Author:

Díaz Marcos¹,Barba Flora²,Miranda Miriam³,Guitián Francisco⁴,Torrecillas Ramón³,Moya José S.¹

Affiliation:

1. Department of Biomaterials and Bioinspired Materials, Instituto de Ciencia de Materiales de Madrid (ICMM-CSIC), Cantoblanco, 28049, Madrid, Spain

2. Department of Ceramic, Instituto de Cerámica y Vidrio (ICV-CSIC), Cantoblanco, 28049, Madrid, Spain

3. Department of Nanostructured Materials, Centro de Investigación en Nanomateriales y Nanotecnología (CINN-CSIC), Francisco Pintado Fe 26, 33011, Oviedo, Spain

4. Instituto de Cerámica de Galicia, Universidad de Santiago de Compostela, 15706, Santiago de Compostela, Spain

Abstract

A silver-hydroxyapatite nanocomposite has been obtained by a colloidal chemical route and subsequent reduction process in H2/Ar atmosphere at350∘C. This material has been characterized by TEM, XRD, and UV-Visible spectroscopy, showing the silver nanoparticles (∼65 nm) supported onto the HA particles (∼130 nm) surface without a high degree of agglomeration. The bactericidal effect against common Gram-positive and Gram-negative bacteria has been also investigated. The results indicated a high antimicrobial activity forStaphylococcus aureus, PneumococcusandEscherichia coli,so this material can be a promising antimicrobial biomaterial for implant and reconstructive surgery applications.

Funder

Spanish Ministry of Education and Science

Publisher

Hindawi Limited

Subject

General Materials Science

Link

http://downloads.hindawi.com/journals/jnm/2009/498505.pdf

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