The Expanding Role of Systemic Therapy in the Management of Hepatocellular Carcinoma-Reference-Cited by-同舟云学术

The Expanding Role of Systemic Therapy in the Management of Hepatocellular Carcinoma

Published:2018-08-07 Issue: Volume:2018 Page:1-4
ISSN:2291-2789
Container-title:Canadian Journal of Gastroenterology and Hepatology
language:en
Short-container-title:Canadian Journal of Gastroenterology and Hepatology

Author:

Abdel-Rahman Omar¹²,Cheung Winson Y.²^ORCID

Affiliation:

1. Clinical Oncology Department, Faculty of Medicine, Ain Shams University, Cairo, Egypt

2. Department of Oncology, University of Calgary, Tom Baker Cancer Centre, Calgary, Alberta, Canada

Abstract

Hepatocellular carcinoma (HCC) represents a global health problem, with the majority of patients presenting at an advanced or incurable stage. The development of effective systemic therapy options for this disease has been challenging because many HCC patients suffer from underlying liver cirrhosis that precludes the safe delivery of systemic therapy. The current review seeks to provide an overview of the current systemic therapeutic approaches for advanced HCC as well as some of the novel management strategies that are currently being evaluated.

Publisher

Hindawi Limited

Subject

Gastroenterology,Hepatology,General Medicine

Link

http://downloads.hindawi.com/journals/cjgh/2018/4763832.pdf

Reference39 articles.

1. Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

2. Epidemiology of Hepatocellular Carcinoma

3. Epidemiology of Hepatocellular Carcinoma in the Asia-Pacific Region

4. Screening for Hepatocellular Carcinoma in Chronic Liver Disease

5. Systemic therapy for hepatocellular carcinoma (HCC): from bench to bedside

Cited by 4 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Egyptian Society of Liver Cancer Recommendation Guidelines for the Management of Hepatocellular Carcinoma;Journal of Hepatocellular Carcinoma;2023-09

2. Yttrium-90 microsphere radioembolisation for unresectable hepatocellular carcinoma;Cochrane Database of Systematic Reviews;2020-01-24

3. Knockdown of interferon‑stimulated gene 15 affects the sensitivity of hepatocellular carcinoma cells to norcantharidin;Experimental and Therapeutic Medicine;2019-09-19

4. Up-Regulation of Phosphatase in Regenerating Liver-3 (PRL-3) Contributes to Malignant Progression of Hepatocellular Carcinoma by Activating Phosphatase and Tensin Homolog Deleted on Chromosome Ten (PTEN)/Phosphoinositide 3-Kinase (PI3K)/AKT Signaling Pathway;Medical Science Monitor;2018-11-12