1. Department of Anaesthesiology and Intensive Therapy, University of Szeged, Semmelweis Utca 6, Szeged 6725, Hungary
2. Department of Anaesthesia, Intensive Care and Pain Medicine, Cardiff University, Institute of Infection and Immunology, Heath Park Campus, Cardiff CF14 4XN, UK
3. Aneurin Bevan University Health Board, Critical Care Directorate, Royal Gwent Hospital, Cardiff Road, Newport NP20 5UB, UK