Hypothalamic Lipoma: Outcome of an Intracranial Developmental Lesion

Author:

Alkhaibary Ali123ORCID,Alsubaie Noura12,Alharbi Ahoud123,Alghanim Noor4,Baydhi Laila5,Khairy Sami123,Musawnaq Fahd23,Alarifi Abdulaziz23,Alwohaibi Mohammed23,Aloraidi Ahmed123,Almuntashri Makki126,Alkhani Ahmed23

Affiliation:

1. College of Medicine, King Saud bin Abdulaziz University for Health Sciences, Riyadh, Saudi Arabia

2. King Abdullah International Medical Research Center, Riyadh, Saudi Arabia

3. Division of Neurosurgery, Department of Surgery, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia

4. College of Medicine, Alfaisal University, Riyadh, Saudi Arabia

5. College of Medicine, Jazan University, Jazan, Saudi Arabia

6. Medical Imaging Department, King Abdulaziz Medical City, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia

Abstract

Background. Hypothalamic lipomas are benign developmental lesions that tend to be discovered incidentally. This article describes the radiological features, outcome, and the postulated theories behind hypothalamic lipomas development. Methods. The electronic archive of neurosurgery was retrospectively reviewed. All patients with a neuroradiological diagnosis of hypothalamic lipoma, between 2005 and 2020, were included. Results. Out of 246 patients with intracranial lipomas, a total of six patients with hypothalamic lipomas have been identified. On computed tomography images, one of the hypothalamic lipomas demonstrated calcification. On magnetic resonance imaging, peripheral enhancement after contrast administration was noted in one of the lesions. Considering the benign nature of the lesions, neurosurgical intervention was not indicated. Conclusion. The majority of patients with hypothalamic lipomas are asymptomatic and undergo brain imaging for other indications. Although uncommon, such developmental lesions can be identified in the general population, especially with the advancement of neuroimaging techniques.

Publisher

Hindawi Limited

Subject

General Earth and Planetary Sciences,Water Science and Technology,Geography, Planning and Development

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