The Role of MRI in Prostate Cancer Active Surveillance

Author:

Johnson Linda M.1,Choyke Peter L.2,Figg William D.13,Turkbey Baris2

Affiliation:

1. Molecular Pharmacology Section, Medical Oncology Branch, National Cancer Institute, Bethesda, MD 20852, USA

2. Molecular Imaging Program, National Cancer Institute, Bethesda, MD 20852, USA

3. Clinical Pharmacology Program, Center for Cancer Research, National Cancer Institute, Bethesda, MD 20852, USA

Abstract

Prostate cancer is the most common cancer diagnosis in American men, excluding skin cancer. The clinical behavior of prostate cancer varies from low-grade, slow growing tumors to high-grade aggressive tumors that may ultimately progress to metastases and cause death. Given the high incidence of men diagnosed with prostate cancer, conservative treatment strategies such as active surveillance are critical in the management of prostate cancer to reduce therapeutic complications of radiation therapy or radical prostatectomy. In this review, we will review the role of multiparametric MRI in the selection and follow-up of patients on active surveillance.

Publisher

Hindawi Limited

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

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