Healthcare Biclustering-Based Prediction on Gene Expression Dataset

Author:

Ramkumar M.1ORCID,Basker N.2,Pradeep D.3,Prajapati Ramesh4,Yuvaraj N.5,Arshath Raja R.5,Suresh C.6,Vignesh Rahul7,Barakkath Nisha U.8,Srihari K.9ORCID,Alene Assefa10ORCID

Affiliation:

1. Department of Computer Science and Engineering, HKBK College of Engineering, India

2. Department of Computer Science and Engineering, Sona College of Technology, India

3. Department of Computer Science and Engineering, M.Kumarasamy College of Engineering, Karur, India

4. Department of Computer Engineering, Shree Swaminarayan Institute of Technology (SSIT), India

5. Research and Publications, ICT Academy, IIT Madras Research Park, India

6. CSE, Sri Ranganathar Institute of Engineering and Technology, Coimbatore, India

7. CSE, Dhanalakshmi Srinivasan College of Engineering, Coimbatore, India

8. IT Department, Sri Krishna College of Engineering and Technology, Coimbatore, India

9. Department of Computer Science and Engineering, SNS College of Technology, India

10. Department of Chemical Engineering, College of Biological and Chemical Engineering, Addis Ababa Science and Technology University, Ethiopia

Abstract

In this paper, we develop a healthcare biclustering model in the field of healthcare to reduce the inconveniences linked to the data clustering on gene expression. The present study uses two separate healthcare biclustering approaches to identify specific gene activity in certain environments and remove the duplication of broad gene information components. Moreover, because of its adequacy in the problem where populations of potential solutions allow exploration of a greater portion of the research area, machine learning or heuristic algorithm has become extensively used for healthcare biclustering in the field of healthcare. The study is evaluated in terms of average match score for nonoverlapping modules, overlapping modules through the influence of noise for constant bicluster and additive bicluster, and the run time. The results show that proposed FCM blustering method has higher average match score, and reduced run time proposed FCM than the existing PSO-SA and fuzzy logic healthcare biclustering methods.

Publisher

Hindawi Limited

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

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