Cerebrovascular Complications and Infective Endocarditis: Impact of Available Evidence on Clinical Outcome

Author:

Schirone Leonardo1ORCID,Iaccarino Alessandra23,Saade Wael4,D’Abramo Mizar4,De Bellis Antonio5,Frati Giacomo16,Sciarretta Sebastiano16,Mestres Carlos-A.7,Greco Ernesto4ORCID

Affiliation:

1. Department of Medico-Surgical Sciences and Biotechnologies, Sapienza University of Rome, Latina, Italy

2. Department of General and Specialistic Surgery “Paride Stefanini”, Sapienza University of Rome, Italy

3. Department of Cardiac Surgery, Humanitas Clinical and Research Center, Rozzano, Milan, Italy

4. Department of Cardiovascular, Respiratory, Nephrological, Anesthesiological, and Geriatric Sciences, Sapienza University of Rome, Italy

5. Department of Cardiology and Cardiac Surgery, Casa di Cura San Michele, Maddaloni, Caserta, Italy

6. IRCCS Neuromed, Pozzilli, Italy

7. Department of Cardiovascular Surgery, University Hospital Zurich, Zurich, Switzerland

Abstract

Background. Infective endocarditis (IE) is a life-threatening disease. Its epidemiological profile has substantially changed in recent years although 1-year mortality is still high. Despite advances in medical therapy and surgical technique, there is still uncertainty on the best management and on the timing of surgical intervention. The objective of this review is to produce further insight into the short- and long-term outcomes of patients with IE, with a focus on those presenting cerebrovascular complications.

Funder

La Sapienza-University of Rome

Publisher

Hindawi Limited

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

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