Chelating Tendencies of Bioactive Aminophosphonates-Reference-Cited by-同舟云学术

Chelating Tendencies of Bioactive Aminophosphonates

Published:1994-01-01 Issue:2-3 Volume:1 Page:247-264
ISSN:0793-0291
Container-title:Metal-Based Drugs
language:en
Short-container-title:Metal-Based Drugs

Author:

Kiss Tamas¹,Lázár István¹,Kafarski Pawel²

Affiliation:

1. Department of Inorganic and Analytical Chemistry, Kossuth Lajos University, P.O. Box 21, Debrecen H -4010, Hungary

2. Institute of Organic and Physical Chemistry, Technical University, Wroclaw PL 50 370, Poland

Abstract

The metal-binding abilities of a wide variety of bioactive aminophosphonates, from the simple aminoethanephosphonic acids to the rather large macrocyclic polyaza derivatives, are discussed with special emphasis on a comparison of the analogous carboxylic acid and phosphonic acid systems. Examples are given of the biological importance of metal ion – aminophosphonate interactions in living systems, and also of their actual and potential applicability in medicine.

Publisher

Hindawi Limited

Subject

Inorganic Chemistry,Drug Discovery,Pharmacology,Toxicology

Link

http://downloads.hindawi.com/archive/1994/704032.pdf

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