Comparison of the Effectiveness of Four Bariatric Surgery Procedures in Obese Patients with Type 2 Diabetes: A Retrospective Study

Author:

Pham Sylvie1,Gancel Antoine1,Scotte Michel2,Houivet Estelle3,Huet Emmanuel2,Lefebvre Hervé14,Kuhn Jean-Marc14,Prevost Gaetan14

Affiliation:

1. Department of Endocrinology, Diabetes and Metabolic Diseases, University Hospital of Rouen, 76031 Rouen, France

2. Department of Digestive Surgery, University Hospital of Rouen, 76031 Rouen, France

3. Department of Biostatistics, University Hospital of Rouen, Institut de Recherche et d’Innovation Biomédicale, Normandie University, 76031 Rouen, France

4. INSERM U982 Neuronal and Neuroendocrine Differentiation and Communication, Institut de Recherche et d’Innovation Biomédicale, Normandie University, University of Rouen, 76821 Mont Saint Aignan, France

Abstract

Aim. The aim of the present retrospective study was to evaluate the efficacy of four bariatric surgical procedures to induce diabetes remission and lower cardiovascular risk factors in diabetic obese patients. Moreover, the influence of surgery on weight evolution in the diabetic population was compared with that observed in a nondiabetic matched population.Methods. Among 970 patients who were operated on in our center since 2001, 81 patients were identified as type 2 diabetes. Laparoscopic adjustable gastric banding (GB), intervention type Mason (MA), gastric bypass (RYGB), and sleeve gastrectomy (SG) were performed, respectively, in 25%, 17%, 28%, and 30% of this diabetic population.Results. The resolution rate of diabetes one year after surgery was significantly higher after SG than GB (62.5% versus 20%,P<0.01), but not significantly different between SG and RYGB. In terms of LDL-cholesterol reduction, RYGB was equivalent to SG and superior to CGMA or GB. Considering the other cardiovascular risk factors, there was no significant difference according to surgical procedures. The weight loss was not statistically different between diabetic and nondiabetic matched patients regardless of the surgical procedures used.Conclusion. Our data confirm that the efficacy of surgery to treat diabetes is variable among the diverse procedures and SG might be an interesting option in this context.

Publisher

Hindawi Limited

Subject

Endocrinology, Diabetes and Metabolism

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