The Effect of TNF-α on CHD and the Relationship between TNF-α Antagonist and CHD in Rheumatoid Arthritis: A Systematic Review-Reference-Cited by-同舟云学术

The Effect of TNF-α on CHD and the Relationship between TNF-α Antagonist and CHD in Rheumatoid Arthritis: A Systematic Review

Published:2022-08-24 Issue: Volume:2022 Page:1-9
ISSN:2090-0597
Container-title:Cardiology Research and Practice
language:en
Short-container-title:Cardiology Research and Practice

Author:

Qian Yezhou¹,Mao Menghui¹,Nian Feige²^ORCID

Affiliation:

1. Department of Cardiology, The First Hospital of Jiaxing, The Affiliated Hospital of Jiaxing University, Jiaxing, China

2. Department of Rheumatology, The First Hospital of Jiaxing, The Affiliated Hospital of Jiaxing University, Jiaxing, China

Abstract

Tumor necrosis factor-alpha (TNF-α) plays an important role in coronary heart disease (CHD), a chronic inflammatory process. Meanwhile, this pro-inflammatory factor is also involved in the pathogenesis of autoimmune diseases such as rheumatoid arthritis (RA). Patients with RA correspond to a higher risk of CHD. TNF-α antagonist, one of the main treatments for RA, may reduce the risk of CHD in patients with RA. This review summarizes the pathogenesis of TNF-α in CHD and discusses the relationship between TNF-α antagonist and CHD in patients with RA.

Funder

Key Medicine Disciplines Co-Construction Project of Jiaxing Municipal

Publisher

Hindawi Limited

Subject

Cardiology and Cardiovascular Medicine

Link

http://downloads.hindawi.com/journals/crp/2022/6192053.pdf

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