Herbal Medicines for Asthmatic Inflammation: From Basic Researches to Clinical Applications

Author:

Liu Fang1ORCID,Xuan Nan-Xia1,Ying Song-Min1,Li Wen1,Chen Zhi-Hua1ORCID,Shen Hua-Hao12ORCID

Affiliation:

1. Department of Respiratory and Critical Care Medicine, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou 310009, China

2. State Key Laboratory of Respiratory Diseases, Guangzhou 510120, China

Abstract

Asthma is one of the most common chronic inflammatory disorders, associated with reversible airflow obstruction, airway hyperresponsiveness, and airway remodeling. This disease has a significant impact on individuals, their families, and society. Standardized therapeutics such as inhaled corticosteroid in combination with long actingβ2 agonist have been applied for asthma control; however, complementary and alternative medicines, especially herbal medicines, are still widely used all over the world. A growing body of literature suggests that various herbals or related products might be effective in inhibiting asthmatic inflammation. In this review, we summarize recent advances about the mechanistic studies of herbal medicines on allergic airway inflammation in animal models and their potential application into clinic for asthma control.

Funder

National Natural Science Foundation of China

Publisher

Hindawi Limited

Subject

Cell Biology,Immunology

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