The Clinical Efficacy of Chemotherapy Combined with Traditional Chinese Medicine in the Treatment of Cervical Cancer and Its Influence on Cellular Immunity, Serum CEA, and TNF-α

Author:

Zhao Qiannan1ORCID,Liu Juanjuan2ORCID,Wang Sai3ORCID,Wang Xiuqin4ORCID,Jiang Xiufang5ORCID

Affiliation:

1. Department of Clinical Laboratory, Yantaishan Hospital, Yantai 26400, China

2. Department of Obstetrics, The Third People’s Hospital of Qingdao, Qingdao 266041, China

3. ICU, Affiliated Qingdao Central Hospital, Qingdao University, Qingdao 266000, China

4. Department of Gynaecology, People’s Hospital of Huakang, Rizhao 276800, China

5. Department of Obstetrics, Zhangqiu District People’s Hospital, Jinan 250200, China

Abstract

Background. This study aims to investigate the clinical efficacy of chemotherapy combined with traditional Chinese medicine in patients with cervical cancer and its effect on cellular immunoglobulin, serum sugar chain antigen 125 (CA125), carcinoembryonic antigen (CEA), and tumor necrosis factor-α (TNF-α). Methods. Conventional chemotherapy was performed in control and observation groups. Meantime, the observation group received traditional Chinese medicine. Finally, the clinical efficacy, immunoglobulin, serum tumor markers, and serum TNF-α of the two groups were compared. Results. Compared with the control group, total effective rate in the observation group was increased. After treatment, serum CD8+, TNF-α, CA125, and CEA levels were reduced in the two groups, and the observation group was higher. In the two groups, CD3+ and CD4+ levels were enhanced after treatment, and the observation group was also higher. Compared with the control group, the immunoglobulin IgG, IgA, and IgM levels increased in the observation group. The incidence of adverse reactions in the observation group was reduced compared to the control group. Conclusion. Chemotherapy combined with traditional Chinese can help improve the clinical efficacy and immunity in patients with cervical cancer. Moreover, the safety and feasibility of the treatment method are relatively high.

Publisher

Hindawi Limited

Subject

Complementary and alternative medicine

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