Affiliation:
1. Rheumatology Department, Pablo Tobón Uribe Hospital, Medellín, Colombia
2. Internal Medicine Department, Fundación Valle del Lili, ICESI University, Cali, Colombia
Abstract
The development of autoimmune disorders requires a combination of genetic, immunological, and environmental factors. Infectious agents, such as viruses and bacteria, can trigger autoimmunity through different mechanisms, and for systemic vasculitis in particular, microbial agents have been suggested to be involved in its pathogenesis. Although the exact mechanisms have not been fully elucidated, different theories have been postulated. This review considers the role of infections in the etiology of primary vasculitis, emphasizing their related immunological events.
Subject
Immunology and Microbiology (miscellaneous),Immunology,Immunology and Allergy
Cited by
17 articles.
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