Reconstruction Using Frozen Autograft for Disseminated Phosphaturic Mesenchymal Tumor of the Humerus after a Pathological Fracture-Reference-Cited by-同舟云学术

Reconstruction Using Frozen Autograft for Disseminated Phosphaturic Mesenchymal Tumor of the Humerus after a Pathological Fracture

Published:2019-09-04 Issue: Volume:2019 Page:1-7
ISSN:2090-6749
Container-title:Case Reports in Orthopedics
language:en
Short-container-title:Case Reports in Orthopedics

Author:

Kobayashi Hiroshi¹^ORCID,Hirai Toshihide¹,Makise Naohiro²,Ushiku Tetsuo²,Ito Nobuaki³,Koga Minae³,Ikegami Masachika¹,Shinoda Yusuke¹^ORCID,Akiyama Toru⁴^ORCID,Tanaka Sakae¹^ORCID

Affiliation:

1. Department of Orthopaedic Surgery, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan

2. Department of Pathology, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan

3. Department of Nephrology and Endocrinology, The University of Tokyo Hospital, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8655, Japan

4. Department of Orthopaedic Surgery, Saitama Medical Center, Jichi Medical University, 1-847 Amanuma, Omiya-ku, Saitama 330-8503, Japan

Abstract

Phosphaturic mesenchymal tumors (PMTs) that cause tumor-induced osteomalacia (TIO) occur commonly in the bone with a small and nonaggressive appearance. Here, we report the case of a 67-year-old man with disseminated PMT in the humerus after a pathological fracture. Liquid nitrogen was used as an adjuvant therapy after curettage of the tumor, and the frozen autograft, using a pedicle freezing method, conserved the function of the shoulder joint. To our knowledge, this is the first case of a disseminated PMT in the bone that was treated with a frozen autograft, and this treatment method may be effective for cases in which curettage for PMT in the bone would be inevitably inadequate.

Publisher

Hindawi Limited

Subject

General Earth and Planetary Sciences,General Environmental Science

Link

http://downloads.hindawi.com/journals/crior/2019/3015675.pdf

Reference11 articles.

1. Tumour-induced osteomalacia

2. Tumor-induced osteomalacia: An important cause of adult-onset hypophosphatemic osteomalacia in China: Report of 39 cases and review of the literature

3. Infiltrative nature of tumor-induced osteomalacia lesions in bone: Correlation between radiological and histopathological features

4. Effects of liquid nitrogen treatment on the proliferation ofosteosarcoma and the biomechanical properties of normal bone

5. Pedicle frozen autograft reconstruction in malignant bone tumors