Combined Papillary Renal Cell Carcinoma with Neuroendocrine Differentiation and Mucinous Tubular and Spindle Cell Carcinoma-Reference-Cited by-同舟云学术

Combined Papillary Renal Cell Carcinoma with Neuroendocrine Differentiation and Mucinous Tubular and Spindle Cell Carcinoma

Published:2018-12-31 Issue: Volume:2018 Page:1-5
ISSN:2090-6781
Container-title:Case Reports in Pathology
language:en
Short-container-title:Case Reports in Pathology

Author:

Wang Gang¹^ORCID,Yuan Ren²,Tucker Tracy¹,Gates Allan B.³,Bellamy Christopher D.⁴,Hayes Malcolm M.¹

Affiliation:

1. Department of Pathology, BC Cancer Vancouver Centre, Vancouver, BC, Canada

2. Department of Radiology, BC Cancer Vancouver Centre, Vancouver, BC, Canada

3. Department of Pathology, Abbotsford Regional Hospital, Abbotsford, BC, Canada

4. North Island Pathology, Comox, BC, Canada

Abstract

A unique case of combined papillary renal cell carcinoma (PRCC) and mucinous tubular and spindle cell carcinoma (MTSCC) presenting in a man aged 67 years is reported. The two separate components were distinct on morphological, immunohistochemical (IHC), and genetic grounds, while type 2 PRCC predominated. Three years after the initial diagnosis, the PRCC component metastasized to the lungs where it morphologically mimicked a pulmonary neuroendocrine tumor. Retrospectively focal neuroendocrine differentiation was demonstrated by IHC in the PRCC component of the primary neoplasm.

Publisher

Hindawi Limited

Subject

General Medicine

Link

http://downloads.hindawi.com/journals/cripa/2018/8734823.pdf

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