Theranostic Imaging of Yttrium-90

Abstract

This paper overviews Yttrium-90 (90Y) as a theranostic and nuclear medicine imaging of90Y radioactivity with bremsstrahlung imaging and positron emission tomography. In addition, detection and optical imaging of90Y radioactivity using Cerenkov luminescence will also be reviewed. Methods and approaches for qualitative and quantitative90Y imaging will be briefly discussed. Although challenges remain for90Y imaging, continued clinical demand for predictive imaging response assessment and target/nontarget dosimetry will drive research and technical innovation to provide greater clinical utility of90Y as a theranostic agent.