MAML2-Rearranged Primary Central Mucoepidermoid Carcinoma of the Mandible as an Incidental Finding: A Case Report and Review of the Literature of Molecularly Confirmed Cases-Reference-Cited by-同舟云学术

MAML2-Rearranged Primary Central Mucoepidermoid Carcinoma of the Mandible as an Incidental Finding: A Case Report and Review of the Literature of Molecularly Confirmed Cases

Published:2023-04-11 Issue: Volume:2023 Page:1-6
ISSN:2090-6455
Container-title:Case Reports in Dentistry
language:en
Short-container-title:Case Reports in Dentistry

Author:

Aguirre Sarah E.¹,Tyler Donald²,Owosho Adepitan A.¹³^ORCID

Affiliation:

1. Department of Diagnostic Sciences, College of Dentistry, The University of Tennessee Health Sciences Center, Memphis, TN, USA

2. Joint Base San Antonio-Lackland Air Force Base, San Antonio, TX, USA

3. Department of Otolaryngology—Head & Neck Surgery, College of Medicine, The University of Tennessee Health Sciences Center, Memphis, TN, USA

Abstract

This report presents an extremely rare case of MAML2-rearranged primary central mucoepidermoid carcinoma (MEC) of the mandible that was discovered as an incidental finding. Our review of the literature identified 36 cases of MAML2-rearranged intraosseous lesions of the jaw (30 central MECs, 5 odontogenic cysts with mucous prosoplasia, and 1 glandular odontogenic cyst). Given the therapeutic indications for a diagnosis of MEC (a malignant neoplasm), MAML2 rearrangement should be confirmed in suspected cases of central MEC.

Publisher

Hindawi Limited

Subject

General Dentistry

Link

http://downloads.hindawi.com/journals/crid/2023/7764292.pdf

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