Quantification of Upper Limb Motor Recovery and EEG Power Changes after Robot-Assisted Bilateral Arm Training in Chronic Stroke Patients: A Prospective Pilot Study

Author:

Gandolfi Marialuisa12ORCID,Formaggio Emanuela3ORCID,Geroin Christian12,Storti Silvia Francesca4ORCID,Boscolo Galazzo Ilaria4ORCID,Bortolami Marta12,Saltuari Leopold56,Picelli Alessandro12ORCID,Waldner Andreas67ORCID,Manganotti Paolo8,Smania Nicola12ORCID

Affiliation:

1. Neuromotor and Cognitive Rehabilitation Research Centre (CRRNC), Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy

2. U.O.C Neurorehabilitation Unit, AOUI of Verona, Verona, Italy

3. San Camillo Hospital IRCCS, Venice, Italy

4. Department of Computer Science, University of Verona, Verona, Italy

5. Department of Neurology, Hochzirl Hospital, 6170 Zirl, Austria

6. Research Unit for Neurorehabilitation South Tyrol, 39100 Bolzano, Italy

7. Department of Neurological Rehabilitation, Private Hospital Villa Melitta, Bolzano, Italy

8. Clinical Unit of Neurology, Department of Medical Sciences, University Hospital and Health Services of Trieste, University of Trieste, Trieste, Italy

Abstract

Background. Bilateral arm training (BAT) has shown promise in expediting progress toward upper limb recovery in chronic stroke patients, but its neural correlates are poorly understood.Objective. To evaluate changes in upper limb function and EEG power after a robot-assisted BAT in chronic stroke patients.Methods. In a within-subject design, seven right-handed chronic stroke patients with upper limb paresis received 21 sessions (3 days/week) of the robot-assisted BAT. The outcomes were changes in score on the upper limb section of the Fugl-Meyer assessment (FM), Motricity Index (MI), and Modified Ashworth Scale (MAS) evaluated at the baseline (T0), posttraining (T1), and 1-month follow-up (T2). Event-related desynchronization/synchronization were calculated in the upper alpha and the beta frequency ranges.Results. Significant improvement in all outcomes was measured over the course of the study. Changes in FM were significant at T2, and in MAS at T1and T2. After training, desynchronization on the ipsilesional sensorimotor areas increased during passive and active movement, as compared with T0.Conclusions. A repetitive robotic-assisted BAT program may improve upper limb motor function and reduce spasticity in the chronically impaired paretic arm. Effects on spasticity were associated with EEG changes over the ipsilesional sensorimotor network.

Funder

James S. McDonnell Foundation

Publisher

Hindawi Limited

Subject

Neurology (clinical),Neurology

Cited by 42 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

同舟云学术

1.学者识别学者识别

2.学术分析学术分析

3.人才评估人才评估

"同舟云学术"是以全球学者为主线,采集、加工和组织学术论文而形成的新型学术文献查询和分析系统,可以对全球学者进行文献检索和人才价值评估。用户可以通过关注某些学科领域的顶尖人物而持续追踪该领域的学科进展和研究前沿。经过近期的数据扩容,当前同舟云学术共收录了国内外主流学术期刊6万余种,收集的期刊论文及会议论文总量共计约1.5亿篇,并以每天添加12000余篇中外论文的速度递增。我们也可以为用户提供个性化、定制化的学者数据。欢迎来电咨询!咨询电话:010-8811{复制后删除}0370

www.globalauthorid.com

TOP

Copyright © 2019-2024 北京同舟云网络信息技术有限公司
京公网安备11010802033243号  京ICP备18003416号-3