A Quantitative Structure-Activity Relationship and Molecular Modeling Study on a Series of Heteroaryl- and Heterocyclyl-Substituted Imidazo[1,2-a]Pyridine Derivatives Acting as Acid Pump Antagonists
Author:
Affiliation:
1. Department of Biotechnology, Meerut Institute of Engineering and Technology, Meerut 250005, India
2. Department of Pharmaceutical Technology and Department of Applied Sciences, Meerut Institute of Engineering and Technology, Meerut 250005, India
Publisher
Hindawi Limited
Subject
Biochemistry
Link
http://downloads.hindawi.com/journals/bri/2013/141469.pdf
Reference19 articles.
1. The Novel Acid Pump Antagonists for Anti-secretory Actions with Their Peculiar Applications Beyond Acid Suppression
2. Novel indanyl-substituted imidazo[1,2-a]pyridines as potent reversible inhibitors of the gastric H+/K+-ATPase
3. Insight into the structural requirements of proton pump inhibitors based on CoMFA and CoMSIA studies
4. Orally active C-6 heteroaryl- and heterocyclyl-substituted imidazo[1,2-a]pyridine acid pump antagonists (APAs)
5. Systematic review: proton-pump inhibitor failure in gastro-oesophageal reflux disease - where next?
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