Lower Lid Reconstruction Utilizing Auricular Conchal Chondral-Perichondral Tissue in Patients with Neoplastic Lesions

Author:

Parodi Pier Camillo1,Calligaris Fabrizio1,De Biasio Fabrizio1,De Maglio Giovanna2,Miani Flavia3,Zeppieri Marco3ORCID

Affiliation:

1. Department of Plastic and Reconstructive Surgery, Azienda Ospedaliero-Universitaria “Santa Maria della Misericordia,” Piazzale S. Maria della Misericordia 15, 33100 Udine, Italy

2. Department of Histopathology, Azienda Ospedaliero-Universitaria “Santa Maria della Misericordia,” Piazzale S. Maria della Misericordia 15, 33100 Udine, Italy

3. Department of Ophthalmology, Azienda Ospedaliero-Universitaria “Santa Maria della Misericordia,” Piazzale S. Maria della Misericordia 15, 33100 Udine, Italy

Abstract

Purpose. To assess surgical outcomes of lower lid reconstruction surgery using auricular conchal tissue.Methods. This prospective study included 20 patients that underwent reconstructive lower lid surgery using autologous auricle chondral-perichondral graft tissue. Auricle tissue was used to provide adequate support and protection with similar conjunctiva tarsal structures on overlying soft tissues in patients with pathologic inferior lid tissue loss requiring reconstructive surgery. Biopsies with histopathology and cytology analysis were taken after 1 year. Cytology analysis using CK19 was used to confirm newly formed conjunctiva overlying the graft.Results. All patients showed no graft rejection. Surgical outcomes were generally good, with minimal or no ocular complications. 16 of 20 patients had excellent results, showing good lid symmetry and esthetics, minimal auricular discomfort, patient satisfaction and proper lid function. Surgical outcomes were highly dependent on proper post-op conjunctiva formation. All patients were positive for CK19, thus indicating proper conjunctiva tissue formation.Conclusions. Lower lid reconstruction surgery using auricular chondral-perichondral conchal tissue is a good alternative in patients with neoplastic lesions. Autologous chondral-perichondral tissue provides good functional and mechanical support in the reconstructed lid, thus reducing the risks of ectropion and corneal exposure and ensuring a protected ocular surface.

Publisher

Hindawi Limited

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

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