Pathophysiological Significance of Hepatic Apoptosis-Reference-Cited by-同舟云学术

Pathophysiological Significance of Hepatic Apoptosis

Published:2013-12-30 Issue: Volume:2013 Page:1-14
ISSN:2314-4041
Container-title:ISRN Hepatology
language:en
Short-container-title:ISRN Hepatology

Author:

Wang Kewei¹,Lin Bingliang²

Affiliation:

1. Departments of Surgery and Pediatrics, University of Illinois College of Medicine at Peoria, Peoria, IL 61605, USA

2. Department of Infectious Diseases, Third Affiliated Hospital of Sun Yat-sen University, Guangzhou 510630, China

Abstract

Apoptosis is a classical pathological feature in liver diseases caused by various etiological factors such as drugs, viruses, alcohol, and cholestasis. Hepatic apoptosis and its deleterious effects exacerbate liver function as well as involvement in fibrosis/cirrhosis and carcinogenesis. An imbalance between apoptotic and antiapoptotic capabilities is a prominent characteristic of liver injury. The regulation of apoptosis and antiapoptosis can be a pivotal step in the treatment of liver diseases.

Publisher

Hindawi Limited

Subject

General Medicine

Link

http://downloads.hindawi.com/archive/2013/740149.pdf

Reference183 articles.

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4. Apoptosis versus necrosis rate as a predictor in acute liver failure following acetaminophen intoxication compared with acute-on-chronic liver failure

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