The Physicochemical Properties of Graphene Nanocomposites Influence the Anticancer Effect

Author:

Yang Wenbo1ORCID,Deng Xiangyu1ORCID,Huang Wei1,Qing Xiangcheng1,Shao Zengwu1ORCID

Affiliation:

1. Department of Orthopaedic Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430022, China

Abstract

Graphene nanocomposite is an inorganic nanocomposite material, which has been widely used in the treatment of tumor at present due to its ability of drug loading, modifiability, photothermal effect, and photodynamic effect. However, the application of graphene nanocomposite is now limited due to the fact that the functions mentioned above are not well realized. This is mainly because people do not have a systematic understanding of the physical and chemical properties of GO nanomolecules, so that we cannot make full use of GO nanomolecules to make the most suitable materials for the use of medicine. Here, we are the first to discuss the influence of the physicochemical properties of graphene nanocomposite on the various functions related to their antitumor effects. The relationship between some important physicochemical properties of graphene nanocomposite such as diameter, shape, and surface chemistry and their functions related to antitumor effects was obtained through analysis, which provides evidence for the application of related materials in the future.

Funder

National Natural Science Foundation of China

Publisher

Hindawi Limited

Subject

Oncology

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