Orbital Infection by Saksenaea vasiformis in an Immunocompetent Host

Author:

Lumyongsatien Mingkwan1ORCID,Jaru-ampornpan Pimkwan2,Uiprasertkul Mongkol3,Selva Dinesh4

Affiliation:

1. Department of Ophthalmology, Mettapracharak Hospital, Sampran District, 52 moo2 Rhikhing, Sampran, Nakhon Pathom, 73210, Thailand

2. Department of Ophthalmology, Faculty of Medicine, Siriraj Hospital, Mahidol University, 2 Arun Amarin Road, Siriraj, Bangkoknoi, Bangkok, 10700, Thailand

3. Department of Pathology, Faculty of Medicine, Siriraj Hospital, Mahidol University, 2 Arun Amarin road, Siriraj, Bangkoknoi, Bangkok, 10700, Thailand

4. Department of Ophthalmology and Visual Sciences, South Australian Institute of Ophthalmology, University of Adelaide, Adelaide, South Australia, Australia

Abstract

Orbital mucormycosis caused by Saksenaea vasiformis is extremely rare. Herein, we report an immunocompetent 22-year-old Thai female who presented with two months of progressive right upper eyelid mass, associated with swelling, redness, and ptosis. She failed to improve despite multiple courses of antibiotic and steroid treatment. Computed tomography (CT) scan showed infiltration involving the upper eyelid and lacrimal gland. Fungal hyphae were revealed by histopathological study. Polymerase chain reaction (PCR) was positive for Saksenaea vasiformis (GenBank: accession number FR687327.1). The patient was successfully treated with surgical debridement, amphotericin B, and oral posaconazole.

Publisher

Hindawi Limited

Subject

Ocean Engineering

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