A Review of the Diagnosis and Treatment of Ochratoxin A Inhalational Exposure Associated with Human Illness and Kidney Disease including Focal Segmental Glomerulosclerosis-Reference-Cited by-同舟云学术

A Review of the Diagnosis and Treatment of Ochratoxin A Inhalational Exposure Associated with Human Illness and Kidney Disease including Focal Segmental Glomerulosclerosis

Published:2012 Issue: Volume:2012 Page:1-10
ISSN:1687-9805
Container-title:Journal of Environmental and Public Health
language:en
Short-container-title:Journal of Environmental and Public Health

Author:

Hope Janette H.¹,Hope Bradley E.²

Affiliation:

1. Environmental Medicine, 304 West Los Olivos Street, Santa Barbara, CA 93105, USA

2. American Indian Health and Services, 4141 State Street B-4, Santa Barbara, CA 93110, USA

Abstract

Ochratoxin A (OTA) exposure via ingestion and inhalation has been described in the literature to cause kidney disease in both animals and humans. This paper reviews Ochratoxin A and its relationship to human health and kidney disease with a focus on a possible association with focal segmental glomerulosclerosis (FSGS) in humans. Prevention and treatment strategies for OTA-induced illness are also discussed, including cholestyramine, a bile-acid-binding resin used as a sequestrant to reduce the enterohepatic recirculation of OTA.

Publisher

Hindawi Limited

Subject

Health, Toxicology and Mutagenesis,Public Health, Environmental and Occupational Health

Link

http://downloads.hindawi.com/journals/jeph/2012/835059.pdf

Reference76 articles.

1. Ochratoxin a: Its Cancer Risk and Potential for Exposure

2. Biochemical Characterization of Ochratoxin A-Producing Strains of the Genus Penicillium

3. Ochratoxins—Food Contaminants: Impact on Human Health

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