Validation and Refinement of the Baveno VI Criteria for Ruling Out High-Risk Varices

Author:

Zhou Hong12ORCID,Hu Han1ORCID,Tian Maoyong3ORCID,Chu Jun1ORCID,Tian Caiyun1ORCID,Yang Yanqing1ORCID,Lin Shide1ORCID

Affiliation:

1. Department of Infectious Diseases, Affiliated Hospital of Zunyi Medical University, 201 Dalian Street, Guizhou 563003, China

2. Department of Infectious Diseases, Suining Central Hospital, 127 Desheng Street, Suining, Sichuan 629000, China

3. Department of Infectious Diseases, Xishui County People’s Hospital, Xiangjiang Street, Xishui, Guizhou 564600, China

Abstract

In the past decade, numerous studies have evaluated the roles of noninvasive methods for diagnosing or excluding varices and high-risk varices in patients with liver cirrhosis. The Baveno VI criteria recommend the use of a simple algorithm based on a liver stiffness measurement < 20 kPa through transient elastography and a platelet count > 150 × 10 9 / L for ruling out high-risk varices in patients with compensated advanced chronic liver disease. A large number of studies have validated the clinical usefulness of Baveno VI criteria for excluding high-risk varices. Several strategies have been proposed to refine the Baveno VI criteria; however, currently there is no review to summarize the diagnostic accuracy and limitations of the Baveno VI criteria after extensive validation. In this review, we summarize the diagnostic accuracy and limitations of the Baveno VI criteria after extensive validation. We also discuss methods to refine these criteria.

Funder

National Natural Science Foundation of China

Publisher

Hindawi Limited

Subject

Gastroenterology,Hepatology

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