Squamous Cell Carcinoma of the Lung with Metastasis to the GI Tract Associated with EGFR Exon 19 Deletion-Reference-Cited by-同舟云学术

Squamous Cell Carcinoma of the Lung with Metastasis to the GI Tract Associated with EGFR Exon 19 Deletion

Published:2013 Issue: Volume:2013 Page:1-2
ISSN:1687-9627
Container-title:Case Reports in Medicine
language:en
Short-container-title:Case Reports in Medicine

Author:

Weiss Glen J.¹²³,Liman Agnes K.⁴⁵,Allen Jeffrey⁶,Cheung Philip Y.²,Kukunoor Rajesh N.⁷

Affiliation:

1. Cancer Treatment Centers of America, Goodyear, AZ 85338, USA

2. The Translational Genomics Research Institute, Phoenix, AZ 85004, USA

3. CRAB Clinical Trials Consortium, Seattle, WA 98101, USA

4. Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, PA 15206, USA

5. University of Pittsburgh School of Medicine, Pittsburgh, PA 15261, USA

6. Humboldt Medical Specialists, Eureka, CA 95501, USA

7. Ironwood Cancer and Research Centers, Phoenix, AZ 85028, USA

Abstract

We describe three confirmed cases of squamous cell carcinoma (SCC) of the lung with metastasis to the gastrointestinal (GI) tract, with two having epidermal growth factor receptor (EGFR) exon 19 deletions in all available specimens. One of these patients received EGFR tyrosine kinase directed therapy for a brief period with some symptom relief. Consideration of EGFR exon 19 mutation testing in SCC of the lung, particularly for those with GI tract metastasis, may identify this potentially drug-targetable entity.

Publisher

Hindawi Limited

Subject

General Medicine

Link

http://downloads.hindawi.com/journals/crim/2013/874836.pdf

Reference5 articles.

1. Colonic metastases from primary squamous cell carcinoma of the lung

2. Gastro-intestinal metastasis of primary lung carcinoma: Clinical presentations and outcome

3. Lung Cancer Presenting With a Solitary Colon Metastasis Detected on Positron Emission Tomography Scan

4. Gastrointestinal Metastasis From Primary Lung Cancer: CT Findings and Clinicopathologic Features

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. A Case of Primary Lung Adenocarcinoma With Metastasis to Colon Harboring EGFR Exon 19 Deletion;Cureus;2024-07-02

2. Efficacy of epidermal growth factor receptor-tyrosine kinase inhibitors for lung squamous carcinomas harboring EGFR mutation: A multicenter study and pooled analysis of published reports;Oncotarget;2017-05-17

3. Progression inference for somatic mutations in cancer;Heliyon;2017-04

4. Efficacy of epidermal growth factor receptor (EGFR)-tyrosine kinase inhibitors (TKIs) in targeted therapy of lung squamous cell carcinoma patients with EGFR mutation: a pooled analysis;Oncotarget;2017-02-25

5. Lung adenocarcinoma harboring L858R and T790M mutations in epidermal growth factor receptor, with poor response to gefitinib: A case report;Oncology Letters;2014-07-04