Simultaneous Determination of Eight Chemical Components in Angelicae Sinensis Radix and Its Herbal Products by QAMS

Author:

Zhang Yu12ORCID,Li Qian1ORCID,Feng Yanmei1,Yang Lan1,Wang Qi1,Guo Yehong1,Qiu Daiyu1

Affiliation:

1. Gansu Provincial Key Laboratory of Aridland Crop Science, College of Agronomy, Gansu Agricultural University, Lanzhou 730070, China

2. Fanjia Zhuozi Health Center Huanglong County, Yanan 715700, China

Abstract

A HPLC method has been developed for simultaneously detecting chlorogenic acid, ferulic acid, senkyunolide I, senkyunolide H, coniferyl ferulate, senkyunolide A, ligustilide, and levistolide A in Angelicae Sinensis Radix through quantitative analysis of multicomponents by single-marker (QAMS) method with ferulic acid as internal standard substance. The relative analysis correction factors of each component in Angelicae Sinensis Radix have good reproducibility under different chromatography conditions. In addition, no significant difference of results was found between quantitative analysis of multicomponents by single-marker (QAMS) method and external standard method in determining content of these components of different Angelicae Sinensis Radix and its 12 kinds of preparations. As a result, the established QAMS method for Angelicae Sinensis Radix analysis with ferulic acid as internal standard substance is accurate and feasible, which could be used as an effective and economical method to control quality of Angelicae Sinensis Radix and its herbal products.

Funder

National Natural Science Foundation of China

Publisher

Hindawi Limited

Subject

Computer Science Applications,Instrumentation,General Chemical Engineering,Analytical Chemistry

Reference26 articles.

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3. Research progresses in the chemistry and pharmacology of Angelica sinensis (Oliv.) Diel;W. H. Huang;China Journal of Chinesemateriamedica,2001

4. Bioactivities of major constituents isolated from Angelica sinensis (Danggui)

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