3D Winding Number: Theory and Application to Medical Imaging

Author:

Becciu Alessandro1,Fuster Andrea1,Pottek Mark2,van den Heuvel Bart1,ter Haar Romeny Bart1ORCID,van Assen Hans1

Affiliation:

1. Department of Biomedical Engineering, Eindhoven University of Technology, 5600 MB Eindhoven, The Netherlands

2. Department of Biology, Kaiserslautern University of Technology, 67653 Kaiserslautern, Germany

Abstract

We develop a new formulation, mathematically elegant, to detect critical points of 3D scalar images. It is based on a topological number, which is the generalization to three dimensions of the 2D winding number. We illustrate our method by considering three different biomedical applications, namely, detection and counting of ovarian follicles and neuronal cells and estimation of cardiac motion from tagged MR images. Qualitative and quantitative evaluation emphasizes the reliability of the results.

Publisher

Hindawi Limited

Subject

Radiology, Nuclear Medicine and imaging

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. The Differential Structure of Images;Mathematical Optics;2012-12-14

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