Natural Products as Adjunctive Treatment for Pancreatic Cancer: Recent Trends and Advancements

Author:

Yue Qingxi12ORCID,Gao Guogang3,Zou Gangyong4,Yu Haiqing5,Zheng Xi26ORCID

Affiliation:

1. Department of Oncology, Shanghai 9th People’s Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China

2. Department of Chemical Biology, Ernest Mario School of Pharmacy, Rutgers, The State University of New Jersey, Piscataway, NJ, USA

3. Department of Cardiothoracic Surgery, Weihai Municipal Hospital, Weihai, Shandong, China

4. Department of Pathology, Weihai Municipal Hospital, Weihai, Shandong, China

5. Department of Internal Medicine, University of Missouri Hospital and Clinics, Columbia, MO, USA

6. Allan H. Conney Laboratory for Anticancer Research, School of Chemical Engineering and Light Industry, Guangdong University of Technology, Guangzhou, China

Abstract

Pancreatic cancer is a type of common malignant tumors with high occurrence in the world. Most patients presented in clinic had pancreatic cancer at advanced stages. Furthermore, chemotherapy or radiotherapy had very limited success in treating pancreatic cancer. Complementary and alternative medicines, such as natural products/herbal medicines, represent exciting adjunctive therapies. In this review, we summarize the recent advances of using natural products/herbal medicines, such as Chinese herbal medicine, in combination with conventional chemotherapeutic agents to treat pancreatic cancer in preclinical and clinical trials.

Funder

National Nature Science Foundation

Publisher

Hindawi Limited

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

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