Lithium Toxicity in the Setting of Nonsteroidal Anti-Inflammatory Medications

Author:

Hassan Syed1,Khalid Fatima1,Alirhayim Zaid1,Amer Syed2

Affiliation:

1. Department of Internal Medicine, Henry Ford Health System, 2799 West Boulevard, Detroit, MI 48202, USA

2. Department of Internal Medicine, Brookdale Hospital and Medical Center, Detroit, MI, USA

Abstract

Lithium toxicity is known to affect multiple organ systems, including the central nervous system. Lithium levels have been used in the diagnosis of toxicity and in assessing response to management. There is evidence that nonsteroidal anti-inflammatory medications (NSAIDs) can increase lithium levels and decrease renal lithium clearance. We present a case of lithium toxicity, which demonstrates this effect and also highlights the fact that lithium levels do not correlate with clinical improvement, especially the neurological deficit.

Publisher

Hindawi Limited

Subject

Nephrology

Cited by 2 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Thiazide diuretics;BMJ;2024-02-05

2. Lithium precipitated acute kidney injury: A rare case report;Archives of Biological Psychiatry;2023-11-09

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