Bardet-Biedl Syndrome with a Kidney Transplant, Esophageal Adenocarcinoma, and Postoperative Complications

Author:

Yankov Georgi1,Mihalova Teodora1,Petkov Rosen1,Mekov Evgeni1ORCID,Yankova Stefka2,Petrov Danail1

Affiliation:

1. Department of Pulmonary Diseases, Medical Faculty, Medical University-Sofia, MHATPD “Sveta Sofia, ” 19, “Acad. Ivan Geshov” Blvd, Bulgaria

2. Department of Nephrology and Hemodialysis “Prof. I. Mitеv, ” Medical Faculty, Medical University-Sofia, 11, “Acad. Ivan Geshov” Blvd, Bulgaria

Abstract

The authors present a rare clinical case of a patient with Bardet-Biedl syndrome and chronic kidney disease, who reached end-stage renal disease (ESRD) and underwent a long-term hemodialysis treatment, during which infections with Hepatitis C Virus (HCV) infection and Cytomegalovirus (CMV) infection were established. Kidney transplantation from an alive unrelated donor was performed. Later, an adenocarcinoma of the esophagus was diagnosed at an early stage, treated surgically with resection of the esophagus and gastroesophagoplasty afterward. Seven months later, a rare complication of the immunosuppressive therapy with Cyclosporin A occurred, which consisted of spontaneous bilateral pleural hemorrhage. The same, as well as the postoperative ventral hernia, was successfully resolved. Concomitant HCV was also treated. Rare autosomal recessive syndrome with severe complications, adenocarcinoma of the esophagus, spontaneous bilateral pleural hemorrhage after the operation, and successful treatment were discussed.

Publisher

Hindawi Limited

Subject

General Earth and Planetary Sciences,Water Science and Technology,Geography, Planning and Development

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