Method of Depression Classification Based on Behavioral and Physiological Signals of Eye Movement

Author:

Li Mi12ORCID,Cao Lei12ORCID,Zhai Qian34,Li Peng12ORCID,Liu Sa12ORCID,Li Richeng12ORCID,Feng Lei34,Wang Gang34,Hu Bin15,Lu Shengfu12ORCID

Affiliation:

1. Department of Automation, Faculty of Information Technology, Beijing University of Technology, Beijing 100124, China

2. The Beijing International Collaboration Base on Brain Informatics and Wisdom Services, Beijing 100124, China

3. The National Clinical Research Center for Mental Disorders & Beijing Key Laboratory of Mental Disorders, Beijing Anding Hospital, Capital Medical University, Beijing, China

4. The Advanced Innovation Center for Human Brain Protection, Capital Medical University, Beijing, China

5. Gansu Provincial Key Laboratory of Wearable Computing, School of Information Science and Engineering, Lanzhou University, Lanzhou, China

Abstract

This paper presents a method of depression recognition based on direct measurement of affective disorder. Firstly, visual emotional stimuli are used to obtain eye movement behavior signals and physiological signals directly related to mood. Then, in order to eliminate noise and redundant information and obtain better classification features, statistical methods (FDR corrected t-test) and principal component analysis (PCA) are used to select features of eye movement behavior and physiological signals. Finally, based on feature extraction, we use kernel extreme learning machine (KELM) to recognize depression based on PCA features. The results show that, on the one hand, the classification performance based on the fusion features of eye movement behavior and physiological signals is better than using a single behavior feature and a single physiological feature; on the other hand, compared with previous methods, the proposed method for depression recognition achieves better classification results. This study is of great value for the establishment of an automatic depression diagnosis system for clinical use.

Funder

National Natural Science Foundation of China

Publisher

Hindawi Limited

Subject

Multidisciplinary,General Computer Science

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