Advanced MR Imaging of Gliomas: An Update

Author:

Kao Hung-Wen12,Chiang Shih-Wei23,Chung Hsiao-Wen23,Tsai Fong Y.45,Chen Cheng-Yu2

Affiliation:

1. Department of Biomedical Imaging and Radiological Sciences, National Yang-Ming University, No. 155, Sec. 2, Linong Street, Taipei 112, Taiwan

2. Department of Radiology, Tri-Service General Hospital, National Defense Medical Center, No. 325, Sec. 2, Cheng-Kong Road, Neihu, Taipei 114, Taiwan

3. Department of Electrical Engineering, National Taiwan University, No. 1, Sec. 4, Roosevelt Road, Taipei 106, Taiwan

4. Imaging Research Center, Taipei Medical University, No. 250, Wu-Hsing Street, Taipei 110, Taiwan

5. Department of Radiological Sciences, University of California at Irvine Medical Center, Irvine, 101 The City Drive South, Orange, CA 92868, USA

Abstract

Recent advances in the treatment of cerebral gliomas have increased the demands on noninvasive neuroimaging for the diagnosis, therapeutic planning, tumor monitoring, and patient outcome prediction. In the meantime, improved magnetic resonance (MR) imaging techniques have shown much potentials in evaluating the key pathological features of the gliomas, including cellularity, invasiveness, mitotic activity, angiogenesis, and necrosis, hence, further shedding light on glioma grading before treatment. In this paper, an update of advanced MR imaging techniques is reviewed, and their potential roles as biomarkers of tumor grading are discussed.

Funder

National Science Council

Publisher

Hindawi Limited

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

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