Beneficial Effects of Combining Computed Tomography Enteroclysis/Enterography with Capsule Endoscopy for Screening Tumor Lesions in the Small Intestine

Author:

Shibata Hiroaki1,Hashimoto Shinichi1,Shimizu Kensaku2,Kawasato Ryo1,Shirasawa Tomohiro1,Yokota Takayuki1,Onoda Hideko2,Okamoto Takeshi1,Nishikawa Jun1ORCID,Matsunaga Naofumi2,Sakaida Isao1

Affiliation:

1. Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube, Yamaguchi 755-8505, Japan

2. Department of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minami-Kogushi, Ube, Yamaguchi 755-8505, Japan

Abstract

Aim. To compare the efficacy of using computed tomography enteroclysis/enterography (CTE), capsule endoscopy (CE), and CTE with CE for diagnosing tumor lesions in the small intestine.Materials and Methods. We included 98 patients who underwent CE during the observation period and were subjected to CTE at our hospital from April 2008 to May 2014.Results. CTE had a significantly higher sensitivity than CE (84.6% versus 46.2%,P=0.039), but there were no significant differences in specificity, positive or negative predictive values, or diagnostic accuracy rates. The sensitivity of CTE/CE was 100%, again significantly higher than that of CEP=0.002. The difference in specificity between CTE/CE and CE was not significant, but there were significant differences in positive predictive values (100% for CTE/CE versus 66.7% for CE,P=0.012), negative predictive values (100% versus 92.1%,P=0.008), and diagnostic accuracy rate (100% versus 89.8%,P=0.001). The diagnostic accuracy rate was also significantly higher in CTE/CE versus CTE (100% versus 95.9%,P=0.043).Conclusion. Our findings suggested that a combination of CTE and CE was useful for screening tumor lesions in the small intestine. This trial is registered with numberUMIN000016154.

Publisher

Hindawi Limited

Subject

Gastroenterology,Hepatology

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