Virulence Genotyping ofPasteurella multocidaIsolated from Multiple Hosts from India

Abstract

In this study, 108P. multocidaisolates recovered from various host animals such as cattle, buffalo, swine, poultry (chicken, duck, and emu) and rabbits were screened for carriage of 8 virulence associated genes. The results revealed some unique information on the prevalence of virulence associated genes among Indian isolates. With the exception oftoxAgene, all other virulence associated genes were found to be regularly distributed among host species. Association study between capsule type and virulence genes suggested thatpfhA, nanB,andnanHgenes were regularly distributed among all serotypes with the exception of CapD, whereastoxAgene was found to be positively associated with CapD and CapA. The frequency ofhgbAandnanHgenes among swine isolates of Indian origin was found to be less in comparison to its equivalents around the globe. Interestingly, very high prevalence oftbpAgene was observed among poultry, swine, and rabbit isolates. Likewise, very high prevalence ofpfhAgene (95.3%) was observed among Indian isolates, irrespective of host species origin.