Outcome Prediction of Hematologic Malignancy in Critically Sick People

Author:

Velmurugan Palanivel1ORCID,Moihanavel Vinayagam12ORCID,Altayar Malik A.3ORCID,Jalal Mohammed M.3,Kabrah Saeed M.4ORCID,Qanash Husam56ORCID,Almashjary Majed N.78,Alshehri Osama M.9,Kunwar Vijay Singh10ORCID

Affiliation:

1. Centre for Materials Engineering and Regenerative Medicine, Bharath Institute of Higher Education and Research, Chennai, 600073 Tamil Nadu, India

2. Department of Mechanical Engineering, Chandigarh University, Mohali-140413, Punjab, India

3. Department of Medical Laboratory Technology, Faculty of Applied Medical Sciences, University of Tabuk, Tabuk, Saudi Arabia

4. Department of Laboratory Medicine, Faculty of Applied Medical Sciences, Umm Al-Qura University, Saudi Arabia

5. Department of Medical Laboratory Science, College of Applied Medical Sciences, University of Ha’il, Hail 55476, Saudi Arabia

6. Molecular Diagnostics and Personalized Therapeutics Unit, University of Ha’il, Hail 55476, Saudi Arabia

7. Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah, Saudi Arabia

8. Hematology Research Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah, Saudi Arabia

9. Department of Clinical Laboratory Sciences, College of Applied Medical Science, Najran University, Najran, Saudi Arabia

10. Department of Biotechnology, Himalayan Whitehouse International College Address, Kathmandu 44600, Nepal

Abstract

People with hematologic malignancies (HM) frequently postulate intensive care unit (ICU) hospitalization due to organ damage caused by the disease process or treatment-related consequences. This study is aimed at looking at mortality and sign factors in adult patients with hematologic malignancy (HM) who have been hospitalized in the ICU. Death was one quality indicator; researchers used a machine learning approach to find determinants of death. As per the study, there have been 206 patients hospitalized in the ICU (mean age: 51.3 ± 13.6 years; 60% male). The average length of stay was three days, with 14.1% requiring extended ICU commitment. ICU death was 45.6% at 30 days, 62.6% at sixty days, and 74.3% at twelve months, rising to 59.2% at thirty days, 62.6% at sixty days, and 74.3% at twelve months. Ventilation systems and vasodilating medication were linked to higher ICU death, but admission to the ICU surgically and experiencing malignancies are linked with lower death rates. Patients with HM who are hospitalized in the ICU have a high mortality rate (45.6%), which rises to 74.3% after a year. Serious illness, postsurgical hospitalization, and malignancy were revealed as determinants of patient outcomes in multivariate analyses.

Funder

Najran University

Publisher

Hindawi Limited

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

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