Eosinophils Reduce Chronic Inflammation in Adipose Tissue by Secreting Th2 Cytokines and Promoting M2 Macrophages Polarization-Reference-Cited by-同舟云学术

Eosinophils Reduce Chronic Inflammation in Adipose Tissue by Secreting Th2 Cytokines and Promoting M2 Macrophages Polarization

Published:2015 Issue: Volume:2015 Page:1-5
ISSN:1687-8337
Container-title:International Journal of Endocrinology
language:en
Short-container-title:International Journal of Endocrinology

Author:

Zhang Yi¹,Yang Peng¹,Cui Ran¹,Zhang Manna¹,Li Hong¹,Qian Chunhua¹,Sheng Chunjun¹,Qu Shen¹,Bu Le¹

Affiliation:

1. Shanghai Tenth People’s Hospital, Tongji University, Shanghai 200072, China

Abstract

Obesity is now recognized as a low-grade, chronic inflammatory disease that is linked to a myriad of disorders including cardiovascular diseases, type 2 diabetes, and liver diseases. Recently it is found that eosinophils accelerate alternative activation macrophage (AAM) polarization by secreting Th2 type cytokines such as interleukin-4 and interleukin-13, thereby reducing metainflammation in adipose tissue. In this review, we focused on the role of eosinophils in regulating metabolic homeostasis and obesity.

Publisher

Hindawi Limited

Subject

Endocrine and Autonomic Systems,Endocrinology,Endocrinology, Diabetes and Metabolism

Link

http://downloads.hindawi.com/journals/ije/2015/565760.pdf

Reference37 articles.

1. Mechanisms linking obesity to insulin resistance and type 2 diabetes

2. Nonalcoholic fatty liver disease: an emerging threat to obese and diabetic individuals

3. Prevalence of Obesity and Trends in the Distribution of Body Mass Index Among US Adults, 1999-2010

4. Tissue–Specific Insulin Signaling, Metabolic Syndrome, and Cardiovascular Disease

5. Inflammation and metabolic disorders

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