Perspectives on Peripheral Neuropathy as a Consequence of Metformin-Induced Vitamin B12 Deficiency in T2DM-Reference-Cited by-同舟云学术

Perspectives on Peripheral Neuropathy as a Consequence of Metformin-Induced Vitamin B12 Deficiency in T2DM

Published:2017 Issue: Volume:2017 Page:1-6
ISSN:1687-8337
Container-title:International Journal of Endocrinology
language:en
Short-container-title:International Journal of Endocrinology

Author:

Ahmed Marwan A.¹^ORCID,Muntingh George L.¹,Rheeder Paul²

Affiliation:

1. Department of Pharmacology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa

2. Department of Internal Medicine, Steve Biko Academic Hospital, University of Pretoria, Pretoria, South Africa

Abstract

Peripheral neuropathy (PN) is a primary complication of type 2 diabetes mellitus (T2DM) and a direct manifestation of vitamin B12 deficiency. Examining the effects of metformin use on PN status became imperative following clinical studies that showed the vitamin B12-lowering effect of the medication. The complexity of the topic and the inconsistency of the results warrant consideration of topic-specific perspectives for better understanding of the available evidence and more appropriate design of future studies.

Publisher

Hindawi Limited

Subject

Endocrine and Autonomic Systems,Endocrinology,Endocrinology, Diabetes and Metabolism

Link

http://downloads.hindawi.com/journals/ije/2017/2452853.pdf

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4. Risk Factors of Vitamin B12 Deficiency in Patients Receiving Metformin

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