Perspectives on Peripheral Neuropathy as a Consequence of Metformin-Induced Vitamin B12 Deficiency in T2DM-Reference-Cited by-同舟云学术

Perspectives on Peripheral Neuropathy as a Consequence of Metformin-Induced Vitamin B12 Deficiency in T2DM

Published:2017 Issue: Volume:2017 Page:1-6
ISSN:1687-8337
Container-title:International Journal of Endocrinology
language:en
Short-container-title:International Journal of Endocrinology

Author:

Ahmed Marwan A.¹^ORCID,Muntingh George L.¹,Rheeder Paul²

Affiliation:

1. Department of Pharmacology, Faculty of Health Sciences, University of Pretoria, Pretoria, South Africa

2. Department of Internal Medicine, Steve Biko Academic Hospital, University of Pretoria, Pretoria, South Africa

Abstract

Peripheral neuropathy (PN) is a primary complication of type 2 diabetes mellitus (T2DM) and a direct manifestation of vitamin B12 deficiency. Examining the effects of metformin use on PN status became imperative following clinical studies that showed the vitamin B12-lowering effect of the medication. The complexity of the topic and the inconsistency of the results warrant consideration of topic-specific perspectives for better understanding of the available evidence and more appropriate design of future studies.

Publisher

Hindawi Limited

Subject

Endocrine and Autonomic Systems,Endocrinology,Endocrinology, Diabetes and Metabolism

Link

http://downloads.hindawi.com/journals/ije/2017/2452853.pdf

Reference42 articles.

1. Diabetic Neuropathies: Update on Definitions, Diagnostic Criteria, Estimation of Severity, and Treatments

2. Prevalence and the associated burden of illness of symptoms of diabetic peripheral neuropathy and diabetic retinopathy

3. The Health Care Costs of Diabetic Peripheral Neuropathy in the U.S.

4. Risk Factors of Vitamin B12 Deficiency in Patients Receiving Metformin

Cited by 22 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Interrelations between metformin administration and vitamin B12 concentrations in a black South African diabetic cohort: a retrospective cohort analysis;Journal of Endocrinology, Metabolism and Diabetes of South Africa;2024-04-05

2. Metformin-Induced Vitamin B12 Deficiency in Patients With Type-2 Diabetes Mellitus;Cureus;2023-10-26

3. A PROSPECTIVE STUDY OF EPIDEMIOLOGICAL FACTORS AND OUTCOME IN PATIENTS OF DIABETIC FOOT WOUND ATTENDING J.A. GROUP OF HOSPITALS: A TERTIARY CARE CENTRE;Asian Journal of Pharmaceutical and Clinical Research;2023-06-07

4. Clinical Pathobiochemistry of Vitamin B12 Deficiency: Improving Our Understanding by Exploring Novel Mechanisms with a Focus on Diabetic Neuropathy;Nutrients;2023-06-01

5. Metformin treatment and risk of diabetic peripheral neuropathy in patients with type 2 diabetes mellitus in Beijing, China;Frontiers in Endocrinology;2023-02-28