The Skeletal Muscle Impedancemetric Characteristics as a Marker for Detection of Functional State of Organism

Author:

Deghoyan Anush1,Simonyan Robert1,Wachtel Howard2,Ayrapetyan Sinerik1

Affiliation:

1. Department of Biomedical Engineering, UNESCO Chair-Life Sciences International Postgraduate Educational Center, 31 Acharyan Street, 0040 Yerevan, Armenia

2. Department of ECE, University of Colorado Boulder, 80309-0425 Colorado, USA

Abstract

Previously it has been shown that cell hydration is a universal and extrasensitive marker for different environmental mediums and functional state of tissue and organism. The comparative study of cell hydration of different organs (brain cortex, liver, and skeletal muscle) at various experimental conditions (microstress, pathology, and different poisons) was realized. It was shown that among tissues of different organs muscle hydration is more sensitive to any change of functional state of organism and environmental medium. The study of correlation between tissue muscle hydration and double-frequency measurement impedance method indicated that the differences between muscle reactive conductivity measured at high frequency (HF) and low frequency (LF) could be an adequate marker for detection of muscle hydration. The animal poisoning, stress, and pathology-induced tissue hydration were accompanied by increase in . The observed close correlation between time-dependent tissue hydration and in different environmental mediums can be a marker for detection of postmortal period as well as for characterizing environmental medium of the corpse.

Publisher

Hindawi Limited

Subject

General Medicine

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