Affiliation:
1. Department of Mathematics, University of Zimbabwe, P.O. Box MP 167 Mount Pleasant, Harare, Zimbabwe
Abstract
To better understand the dynamics of zoonotic diseases, we propose a deterministic mathematical model to study the dynamics of zoonotic brucellosis with a focus on developing countries. The model contains all the relevant biological details, including indirect transmission by the environment. We analyze the essential dynamic behavior of the model and perform an optimal control study to design effective prevention and intervention strategies. The sensitivity analysis of the model parameters is performed. The aim of the controls is tied to reducing the number of infected humans, through health promotional programs within the affected communities. The Pontryagin’s Maximum Principle is used to characterize the optimal level of the controls, and the resulting optimality system is solved numerically. Overall, the study demonstrates that through health promotional programs on zoonotic diseases among villagers, it is vital that they should be conducted with high efficacy.
Subject
Applied Mathematics,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Modeling and Simulation,General Medicine
Cited by
13 articles.
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