Female Genital Tuberculosis: Clinical Presentation, Current Diagnosis, and Treatment

Author:

Tjahyadi Dian12ORCID,Ropii Bejo3ORCID,Tjandraprawira Kevin Dominique12ORCID,Parwati Ida4ORCID,Djuwantono Tono1ORCID,Permadi Wiryawan1ORCID,Li Tinchiu5ORCID

Affiliation:

1. Department of Obstetrics & Gynaecology, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia

2. Bandung Fertility Center, Limijati Women and Children Hospital, Bandung, Indonesia

3. Biomedical Engineering Research Group, School of Electrical Engineering and Informatics, Bandung Institute of Technology, Bandung, Indonesia

4. Department of Clinical Pathology, Faculty of Medicine, Padjadjaran University, Bandung, Indonesia

5. Assisted Reproductive Technology Unit Prince of Wales Hospital, Chinese University of Hong Kong, Central Ave, Hong Kong

Abstract

Female genital tuberculosis is a disease caused by Mycobacterium tuberculosis infection in the female reproductive tract. The disease burden among women leads to infertility is significant, especially in developing countries. The bacteria can spread from the lung into the reproductive organ through lymphatic or hematogenous. Many patients present with atypical symptoms, which mimic other gynecological conditions. Several investigations are needed to establish the diagnosis. Almost all cases of genital TB affect the fallopian tube and cause infertility in patients and endometrial involvement. Current treatment still relies on antituberculosis therapy with a combination of tubal surgery. The present review describes the epidemiological data, clinical presentation, diagnosis, and currently available treatment to cure the disease and for in vitro fertilization.

Publisher

Hindawi Limited

Subject

Infectious Diseases,Obstetrics and Gynecology,Dermatology

Reference34 articles.

1. Global Epidemiology of Tuberculosis and Progress Toward Achieving Global Targets — 2017

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3. Female genital tuberculosis: a clinicopathological report of 13 cases

4. Investigation of the prevalence of female genital tract tuberculosis and its relation to female infertility:an observational analytical study;S. Shahzad;Iranian journal of reproductive medicine,2012

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