A Rare Cause of Reversible Renal Hemosiderosis-Reference-Cited by-同舟云学术

A Rare Cause of Reversible Renal Hemosiderosis

Published:2015 Issue: Volume:2015 Page:1-4
ISSN:2090-6641
Container-title:Case Reports in Nephrology
language:en
Short-container-title:Case Reports in Nephrology

Author:

Abou Arkoub Rima¹,Wang Don²,Zimmerman Deborah³

Affiliation:

1. Division of nephrology, The Ottawa Hospital, Ottawa, ON, Canada K1H 7W9

2. Division of Anatomical Pathology, Department of Pathology and Laboratory Medicine, The Ottawa Hospital and Kidney Research Centre of the Ottawa Hospital Research Institute, University of Ottawa, Ottawa, ON, Canada K1H 7W9

3. Division of Nephrology, The Ottawa Hospital and University of Ottawa, Ottawa, ON, Canada K1H 7W9

Abstract

Kidney failure secondary to renal hemosiderosis has been reported in diseases with intravascular hemolysis, like paroxysmal nocturnal hemoglobinuria, and valvular heart diseases. We present here a case of hemosiderin induced acute tubular necrosis secondary to intravascular hemolysis from Clostridium difficile infection with possible role of supratherapeutic INR. We discuss the pathophysiology, causes, and prognosis of acute tubular injury from hemosiderosis.

Publisher

Hindawi Limited

Subject

Nephrology

Link

http://downloads.hindawi.com/journals/crin/2015/464059.pdf

Reference14 articles.

1. Reversible Acute Kidney Injury Caused by Paroxysmal Nocturnal Hemoglobinuria

2. Iron deposition in renal biopsy specimens from patients with kidney diseases

3. Intracellular targets in heme protein-induced renal injury

4. Renal Hemosiderosis in the Hemolytic Anemias: Diagnosis by Means of Needle Biopsy

5. Renal Involvement in Paroxysmal Nocturnal Hemoglobinuria

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