Affiliation:
1. Lehrstuhl für Mikrobiologie, Friedrich-Alexander-Universität Erlangen-Nürnberg, Staudtstrβe 5, 91058 Erlangen, Germany
Abstract
To date the genusCorynebacteriumcomprises 88 species. More than half of these are connected to human and animal infections, with the most prominent member of the pathogenic species beingCorynebacterium diphtheriae, which is also the type species of the genus.Corynebacteriumspecies are characterized by a complex cell wall architecture: the plasma membrane of these bacteria is followed by a peptidoglycan layer, which itself is covalently linked to a polymer of arabinogalactan. Bound to this, an outer layer of mycolic acids is found which is functionally equivalent to the outer membrane of Gram-negative bacteria. As final layer, free polysaccharides, glycolipids, and proteins are found. The composition of the different substructures of the corynebacterial cell envelope and their influence on pathogenicity are discussed in this paper.
Subject
Management, Monitoring, Policy and Law,Geography, Planning and Development
Cited by
63 articles.
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